Search results

• 2024

  BK channels promote action potential repolarization in skeletal muscle but contribute little to myotonia

  Dupont, C., Blake, B., Voss, A. A. & Rich, M. M., 2024, (Accepted/In press) In: Pflugers Archiv European Journal of Physiology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Mechanosensory encoding in ex vivo muscle–nerve preparations

  Housley, S. N., Gardolinski, E. A., Nardelli, P., Reed, J., Rich, M. M. & Cope, T. C., Jan 1 2024, In: Experimental Physiology. 109, 1, p. 35-44 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
• 2023

  A spinal muscular atrophy modifier implicates the SMN protein in SNARE complex assembly at neuromuscular synapses

  Kim, J. K., Jha, N. N., Awano, T., Caine, C., Gollapalli, K., Welby, E., Kim, S. S., Fuentes-Moliz, A., Wang, X., Feng, Z., Sera, F., Takeda, T., Homma, S., Ko, C. P., Tabares, L., Ebert, A. D., Rich, M. M. & Monani, U. R., May 3 2023, In: Neuron. 111, 9, p. 1423-1439.e4

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Plateau potentials contribute to myotonia in mouse models of myotonia congenita

  Wang, X., Dupont, C., Grant, D., Voss, A. A. & Rich, M. M., Mar 2023, In: Experimental Neurology. 361, 114303.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2022

  Diverging from the Norm: Reevaluating What Miniature Excitatory Postsynaptic Currents Tell Us about Homeostatic Synaptic Plasticity

  Koesters, A. G., Rich, M. M. & Engisch, K. L., Jul 29 2022, In: The Neuroscientist.

  Research output: Contribution to journal › Article › peer-review

• Homeostatic Plasticity of the Mammalian Neuromuscular Junction

  Engisch, K. L., Wang, X. & Rich, M. M., 2022, Advances in Neurobiology. Springer, p. 111-130 20 p. (Advances in Neurobiology; vol. 28).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Imbalanced Subthreshold Currents Following Sepsis and Chemotherapy: A Shared Mechanism Offering a New Therapeutic Target?

  Rich, M. M., Housley, S. N., Nardelli, P., Powers, R. K. & Cope, T. C., Apr 1 2022, In: The Neuroscientist. 28, 2, p. 103-120 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Retraction Note: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

  Foust, K. D., Wang, X., McGovern, V. L., Braun, L., Bevan, A. K., Haidet, A. M., Le, T. T., Morales, P. R., Rich, M. M., Burghes, A. H. M. & Kaspar, B. K., Nov 2022, In: Nature Biotechnology. 40, 11, p. 1692 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• The role of action potential changes in depolarization-induced failure of excitation contraction coupling in mouse skeletal muscle

  Wang, X., Nawaz, M., Dupont, C., Myers, J. H., Burke, S. R. A., Bannister, R. A., Foy, B. D., Voss, A. A. & Rich, M. M., 2022, In: eLife. 11, e71588.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2021

  Acetylcholine receptor subunit expression in Huntington's disease mouse muscle

  Simpson, B., Rich, M. M., Voss, A. A. & Talmadge, R. J., Dec 2021, In: Biochemistry and Biophysics Reports. 28, 101182.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• A Mouse Model of Huntington’s Disease Shows Altered Ultrastructure of Transverse Tubules in Skeletal Muscle Fibers

  Romer, S. H., Metzger, S., Peraza, K., Wright, M. C., Jobe, D. S., Song, L. S., Rich, M. M., Foy, B., Talmadge, R. J. & Voss, A. A., Apr 5 2021, In: Journal of General Physiology. 153, 4, e202012637.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Correction to: Profiling age-related muscle weakness and wasting: neuromuscular junction transmission as a driver of age-related physical decline (GeroScience, (2021), 43, 3, (1265-1281), 10.1007/s11357-021-00369-3)

  Padilla, C. J., Harrigan, M. E., Harris, H., Schwab, J. M., Rutkove, S. B., Rich, M. M., Clark, B. C. & Arnold, W. D., Dec 2021, In: GeroScience. 43, 6, p. 2835-2836 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Profiling age-related muscle weakness and wasting: neuromuscular junction transmission as a driver of age-related physical decline

  Padilla, C. J., Harrigan, M. E., Harris, H., Schwab, J. M., Rutkove, S. B., Rich, M. M., Clark, B. C. & Arnold, W. D., Jun 2021, In: GeroScience. 43, 3, p. 1265-1281 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• The mechanism underlying transient weakness in myotonia congenita

  Myers, J. H., Denman, K., Dupont, C., Hawash, A. A., Novak, K. R., Koesters, A., Grabner, M., Dayal, A., Voss, A. A. & Rich, M. M., Apr 27 2021, In: eLife. 10, e65691.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• The Role of Action Potential Waveform in Failure of Excitation Contraction Coupling

  Wang, X., Nawaz, M., Burke, S. R. A., Bannister, R., Foy, B. D., Voss, A. A. & Rich, M. M., Jun 30 2021, In: bioRxiv.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2020

  Central Role of Subthreshold Currents in Myotonia

  Metzger, S., Dupont, C., Voss, A. A. & Rich, M. M., Feb 27 2020, In: Annals of Neurology. 87

  Research output: Contribution to journal › Article › peer-review

• Chronic Defects in Intraspinal Mechanisms of Spike Encoding by Spinal Motoneurons Following Chemotherapy

  Housley, S. N., Nardelli, P., Powers, R. K., Rich, M. M. & Cope, T. C., Sep 1 2020, In: Experimental Neurology. 331

  Research output: Contribution to journal › Article › peer-review

• Depressed Neuromuscular Transmission Causes Weakness in Mice Lacking BK Potassium Channels

  Wang, X., Burke, S. R. A., Talmadge, R. J., Voss, A. A. & Rich, M. M., May 4 2020, In: Journal of General Physiology. 152

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Mechanisms of altered skeletal muscle action potentials in the R6/2 mouse model of Huntington's disease

  Miranda, D. R., Reed, E., Jama, A., Bottomley, M., Ren, H., Rich, M. M. & Voss, A. A., Jul 2020, In: American Journal of Physiology - Cell Physiology. 319, 1, p. C218-C232

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Neuromuscular junction transmission failure is a late phenotype in aging mice

  Chugh, D., Iyer, C. C., Wang, X., Bobbili, P., Rich, M. M. & Arnold, W. D., Feb 1 2020, In: Neurobiology of Aging. 86, p. 182-190 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia

  Ham, D. J., Börsch, A., Lin, S., Thürkauf, M., Weihrauch, M., Reinhard, J. R., Delezie, J., Battilana, F., Wang, X., Kaiser, M. S., Guridi, M., Sinnreich, M., Rich, M. M., Mittal, N., Tintignac, L. A., Handschin, C., Zavolan, M. & Rüegg, M. A., Dec 1 2020, In: Nature Communications. 11, 1, 4510.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• TRPV4 Antagonism Prevents Mechanically Induced Myotonia

  Dupont, C., Novak, K., Denman, K., Myers, J. H., Sullivan, J. M., Walker, P. V., Brown, N. L., Ladle, D. R., Bogdanik, L., Lutz, C. M., A. Voss, A., Sumner, C. J., Rich, M. M. & Denman, K., Aug 1 2020, In: Annals of Neurology. 88, 2, p. 297-308 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2019

  Alteration of T-Tubular Architecture and Capacitance Changes in Huntington's Disease

  Metzger, S. K., Romer, S., Rich, M. M. & Voss, A. A., Feb 1 2019, In: Biophysical Journal. 116

  Research output: Contribution to journal › Article › peer-review

• Open-label trial of ranolazine for the treatment of paramyotonia congenita

  Lorusso, S., Kline, D., Bartlett, A., Freimer, M., Agriesti, J., Hawash, A. A., Rich, M. M., Kissel, J. T. & David Arnold, W., Feb 1 2019, In: Muscle and Nerve. 59, 2, p. 240-243 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Treatment of myotonia congenita with retigabine in mice

  Dupont, C., Denman, K. S., Hawash, A. A., Voss, A. A. & Rich, M. M., May 1 2019, In: Experimental Neurology. 315, p. 52-59 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2018

  Homeostatic synaptic plasticity at the neuromuscular junction in myasthenia gravis

  Wang, X. & Rich, M. M., Jan 1 2018, In: Annals of the New York Academy of Sciences. 1412, 1, p. 170-177 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Muscle Nicotinic Acetylcholine Receptors May Mediate Trans-Synaptic Signaling at the Mouse Neuromuscular Junction

  Wang, X., McIntosh, J. M. & Rich, M. M., Feb 14 2018, In: The Journal of Neuroscience. 38, p. 1725-1736

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2017

  Depressed Synaptic Transmission and Reduced Vesicle Release Sites in Huntington's Disease Neuromuscular Junctions

  Khedraki, A., Reed, E. J., Romer, S. H., Wang, Q., Romine, W., Rich, M. M., Talmadge, R. J. & Voss, A. A., Aug 23 2017, In: Journal of Neuroscience. 37, 34, p. 8077-8091

  Research output: Contribution to journal › Article › peer-review

• Distinct roles for motor neuron autophagy early and late in the SOD1^G93A mouse model of ALS

  Rudnick, N. D., Griffey, C. J., Guarnieri, P., Gerbino, V., Wang, X., Piersaint, J. A., Tapia, J. C., Rich, M. M. & Maniatis, T., Sep 26 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 39, p. E8294-E8303

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Erratum to “A novel path to chronic proprioceptive disability with oxaliplatin: Distortion of sensory encoding” [Neurobiol. Dis. 95 (2016) 54–65](S0969996116301620)(10.1016/j.nbd.2016.07.004)

  Vincent, J. A., Wieczerzak, K. B., Gabriel, H. M., Nardelli, P., Rich, M. M. & Cope, T. C., Feb 1 2017, In: Neurobiology of Disease. 98, p. 158 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Increasing Motor Neuron Excitability to Treat Weakness in Sepsis

  Nardelli, P., Powers, R., Cope, T. C. & Rich, M. M., Dec 1 2017, In: Annals of Neurology. 82

  Research output: Contribution to journal › Article › peer-review

• Inhibiting persistent inward sodium currents prevents myotonia

  Hawash, A. A., Voss, A. A. & Rich, M. M., Sep 1 2017, In: Annals of Neurology. 82, 3, p. 385-395 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Open-label trial of ranolazine for the treatment of myotonia congenita

  Arnold, W. D., Kline, D., Sanderson, A., Hawash, A. A., Bartlett, A., Novak, K. R., Rich, M. M. & Kissel, J. T., Aug 15 2017, In: Neurology. 89, 7, p. 710-713 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2016

  A novel path to chronic proprioceptive disability with oxaliplatin: Distortion of sensory encoding

  Vincent, J. A., Wieczerzak, K. B., Gabriel, H. M., Nardelli, P., Rich, M. M. & Cope, T. C., Nov 1 2016, In: Neurobiology of Disease. 95, p. 54-65 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Reduced Motor Neuron Excitability is an Important Contributor to Weakness in a Rat Model of Sepsis

  Nardelli, P., Vincent, J. A., Powers, R. K., Cope, T. C. & Rich, M. M., Aug 1 2016, In: Experimental Neurology. 282

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Reversible recruitment of a homeostatic reserve pool of synaptic vesicles underlies rapid homeostatic plasticity of quantal content

  Wang, X., Pinter, M. J. & Rich, M. M., Jan 20 2016, In: Journal of Neuroscience. 36, 3, p. 828-836 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2015

  Distinct muscle apoptotic pathways are activated in muscles with different fiber types in a rat model of critical illness myopathy

  Barnes, B. T., Confides, A. L., Rich, M. M. & Dupont-Versteegden, E. E., Jun 18 2015, In: Journal of Muscle Research and Cell Motility. 36, 3, p. 243-253 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Plastin 3 expression does not modify spinal muscular atrophy severity in the Δ7 SMA mouse

  McGovern, V. L., Massoni-Laporte, A., Wang, X., Le, T. T., Le, H. T., Beattie, C. E., Rich, M. M. & Burghes, A. H. M., Jul 2 2015, In: PLoS ONE. 10, 7, e0132364.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Sodium channel slow inactivation as a therapeutic target for myotonia congenita

  Novak, K. R., Norman, J., Mitchell, J. R., Pinter, M. J. & Rich, M. M., Feb 1 2015, In: Annals of Neurology. 77, 2, p. 320-332 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• The sick and the weak: Neuropathies/ myopathies in the critically ill

  Friedrich, O., Reid, M. B., Van Den Berghe, G., Vanhorebeek, I., Hermans, G., Rich, M. M. & Larsson, L., Jul 1 2015, In: Physiological Reviews. 95, 3, p. 1025-1109 85 p., A09.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2014

  An official american thoracic society clinical practice guideline: The diagnosis of intensive care unit-acquired weakness in adults

  Fan, E., Cheek, F., Chlan, L., Gosselink, R., Hart, N., Herridge, M. S., Hopkins, R. O., Hough, C. L., Kress, J. P., Latronico, N., Moss, M., Needham, D. M., Rich, M. M., Stevens, R. D., Wilson, K. C., Winkelman, C., Zochodne, D. W. & Ali, N. A., Dec 15 2014, In: American Journal of Respiratory and Critical Care Medicine. 190, 12, p. 1437-1446 10 p.

  Research output: Contribution to journal › Article › peer-review

• Decreased Cardiac Excitability Secondary to Reduction of Sodium Current May Be a Significant Contributor to Reduced Contractility in a Rat Model of Sepsis

  Koesters, A. G., Engisch, K. L. & Rich, M. M., Jan 1 2014, In: Critical Care. 18

  Research output: Contribution to journal › Article › peer-review
• 2013

  Rabbit supraspinatus motor endplates are unaffected by a rotator cuff tear

  Gayton, J. C., Rubino, L. J., Rich, M. M., Stouffer, M. H., Wang, Q. & Boivin, G. P., Jan 1 2013, In: Journal of Orthopaedic Research. 31, 1, p. 99-104 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Reduced motoneuron excitability in a rat model of sepsis

  Nardelli, P., Khan, J., Powers, R., Cope, T. C. & Rich, M. M., 2013, In: Journal of Neurophysiology. 109, 7, p. 1775-1781 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2012

  Altered sodium channel-protein associations in critical illness myopathy

  Kraner, S. D., Novak, K. R., Wang, Q., Peng, J. & Rich, M. M., Aug 30 2012, In: Skeletal Muscle. 2, 1, 17.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Motor terminal degeneration unaffected by activity changes in SOD1^G93A mice; a possible role for glycolysis

  Carrasco, D. I., Bichler, E. K., Rich, M. M., Wang, X., Seburn, K. L. & Pinter, M. J., Oct 1 2012, In: Neurobiology of Disease. 48, 1, p. 132-140 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Probing risk factors and causes of weakness in critically ill Patients

  Rich, M. M., Jan 1 2012, In: Critical Care Medicine. 40, 1, p. 314-315 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• SMN May Have Multiple Functions Necessitating Widespread Restoration for Maximal Therapeutic Benefit in SMA

  Martinez, T. L., Kong, L., Van Meerbeke, J. P., Gibbs, R., Davis, C., Plaster, H. L., Ko, C. P., Rusche, J. R., Lutz, C. M., Rich, M. M. & Sumner, C. J., Jan 1 2012

  Research output: Other contribution

• Survival motor neuron protein in motor neurons determines synaptic integrity in spinal muscular atrophy

  Martinez, T. L., Kong, L., Wang, X., Osborne, M. A., Crowder, M. E., Van Meerbeke, J. P., Xu, X., Davis, C., Wooley, J., Goldhamer, D. J., Lutz, C. M., Rich, M. M. & Sumner, C. J., Jun 20 2012, In: Journal of Neuroscience. 32, 25, p. 8703-8715 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Survival Motor Neuron Protein in Motor Neurons Determines Synaptic Integrity in Spinal Muscular Atrophy

  Martinez, T. L., Kong, L., Wang, X., Osborne, M. A., Crowder, M. E., Van Meerbeke, J. P., Yu, X., Davis, C., Wooley, J., Goldhamer, D. J., Lutz, C. M., Rich, M. M. & Sumner, C. J., Jun 20 2012, In: The Journal of Neuroscience. 32

  Research output: Contribution to journal › Article › peer-review