A Comparison of Codon Usage Trends in Prokaryotes

Amanda L. Hanes; Michael L. Raymer; Travis E. Doom; Dan E. Krane

doi:10.1109/OCCBIO.2009.26

A Comparison of Codon Usage Trends in Prokaryotes

Amanda L. Hanes, Michael L. Raymer, Travis E. Doom, Dan E. Krane

Research output: Contribution to conference › Poster

Abstract

Codon usage bias is an effective measure of the differences among organisms at a genomic level. These genomic differences also reflect some differences in the organisms’ lifestyles and physiology. Here we demonstrate that prokaryotic obligate intracellular parasites and symbionts have a codon usage pattern that differs significantly from that of exclusively free-living prokaryotes. This result is valuable in that it suggests that the habitat of an organism may directly influence that organism’s use of synonymous codons, which in turn demonstrates evidence of an evolutionary mechanism that operates at a finer molecular level than that of amino acids and proteins.

Original language	American English
DOIs	https://doi.org/10.1109/OCCBIO.2009.26
State	Published - Jun 1 2009
Event	Proceedings of the Ohio Collaborative Conference on Bioinformatics, 2009 - Duration: Jun 1 2009 → …

Conference

Conference	Proceedings of the Ohio Collaborative Conference on Bioinformatics, 2009
Period	6/1/09 → …

Disciplines

Bioinformatics
Communication
Communication Technology and New Media
Computer Sciences
Databases and Information Systems
Life Sciences
OS and Networks
Physical Sciences and Mathematics
Science and Technology Studies
Social and Behavioral Sciences

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10.1109/OCCBIO.2009.26License: CC BY

Cite this

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title = "A Comparison of Codon Usage Trends in Prokaryotes",

abstract = " Codon usage bias is an effective measure of the differences among organisms at a genomic level. These genomic differences also reflect some differences in the organisms{\textquoteright} lifestyles and physiology. Here we demonstrate that prokaryotic obligate intracellular parasites and symbionts have a codon usage pattern that differs significantly from that of exclusively free-living prokaryotes. This result is valuable in that it suggests that the habitat of an organism may directly influence that organism{\textquoteright}s use of synonymous codons, which in turn demonstrates evidence of an evolutionary mechanism that operates at a finer molecular level than that of amino acids and proteins.",

author = "Hanes, {Amanda L.} and Raymer, {Michael L.} and Doom, {Travis E.} and Krane, {Dan E.}",

year = "2009",

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T1 - A Comparison of Codon Usage Trends in Prokaryotes

AU - Hanes, Amanda L.

AU - Raymer, Michael L.

AU - Doom, Travis E.

AU - Krane, Dan E.

PY - 2009/6/1

Y1 - 2009/6/1

N2 - Codon usage bias is an effective measure of the differences among organisms at a genomic level. These genomic differences also reflect some differences in the organisms’ lifestyles and physiology. Here we demonstrate that prokaryotic obligate intracellular parasites and symbionts have a codon usage pattern that differs significantly from that of exclusively free-living prokaryotes. This result is valuable in that it suggests that the habitat of an organism may directly influence that organism’s use of synonymous codons, which in turn demonstrates evidence of an evolutionary mechanism that operates at a finer molecular level than that of amino acids and proteins.

AB - Codon usage bias is an effective measure of the differences among organisms at a genomic level. These genomic differences also reflect some differences in the organisms’ lifestyles and physiology. Here we demonstrate that prokaryotic obligate intracellular parasites and symbionts have a codon usage pattern that differs significantly from that of exclusively free-living prokaryotes. This result is valuable in that it suggests that the habitat of an organism may directly influence that organism’s use of synonymous codons, which in turn demonstrates evidence of an evolutionary mechanism that operates at a finer molecular level than that of amino acids and proteins.

UR - https://corescholar.libraries.wright.edu/knoesis/531

U2 - 10.1109/OCCBIO.2009.26

DO - 10.1109/OCCBIO.2009.26

M3 - Poster

T2 - Proceedings of the Ohio Collaborative Conference on Bioinformatics, 2009

Y2 - 1 June 2009

ER -

A Comparison of Codon Usage Trends in Prokaryotes

Abstract

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