A randomized 2x2 factorial clinical trial of renal transplantation: Steroid-free maintenance immunosuppression with calcineurin inhibitor withdrawal after six months associates with improved renal function and reduced chronic histopathology

R. Brian Stevens; Kirk W. Foster; Clifford D. Miles; Andre C. Kalil; Diana F. Florescu; John P. Sandoz; Theodore H. Rigley; Tamer Malik; Lucile E. Wrenshall

doi:10.1371/journal.pone.0139247

A randomized 2x2 factorial clinical trial of renal transplantation: Steroid-free maintenance immunosuppression with calcineurin inhibitor withdrawal after six months associates with improved renal function and reduced chronic histopathology

R. Brian Stevens, Kirk W. Foster, Clifford D. Miles, Andre C. Kalil, Diana F. Florescu, John P. Sandoz, Theodore H. Rigley, Tamer Malik, Lucile E. Wrenshall

Wright State University

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	e0139247
Journal	PLoS ONE
Volume	10
Issue number	10
DOIs	https://doi.org/10.1371/journal.pone.0139247
State	Published - Oct 14 2015

ASJC Scopus Subject Areas

General

Disciplines

Medical Specialties
Medicine and Health Sciences
Surgery

Access to Document

10.1371/journal.pone.0139247

A Randomized 2x2 Factorial Clinical Trial of Renal TransplantatioFinal published version, 1.8 MBLicense: Unspecified

Cite this

Stevens, R. B., Foster, K. W., Miles, C. D., Kalil, A. C., Florescu, D. F., Sandoz, J. P., Rigley, T. H., Malik, T., & Wrenshall, L. E. (2015). A randomized 2x2 factorial clinical trial of renal transplantation: Steroid-free maintenance immunosuppression with calcineurin inhibitor withdrawal after six months associates with improved renal function and reduced chronic histopathology. PLoS ONE, 10(10), Article e0139247. https://doi.org/10.1371/journal.pone.0139247

A randomized 2x2 factorial clinical trial of renal transplantation: Steroid-free maintenance immunosuppression with calcineurin inhibitor withdrawal after six months associates with improved renal function and reduced chronic histopathology. / Stevens, R. Brian; Foster, Kirk W.; Miles, Clifford D. et al.
In: PLoS ONE, Vol. 10, No. 10, e0139247, 14.10.2015.

Research output: Contribution to journal › Article › peer-review

Stevens, RB, Foster, KW, Miles, CD, Kalil, AC, Florescu, DF, Sandoz, JP, Rigley, TH, Malik, T & Wrenshall, LE 2015, 'A randomized 2x2 factorial clinical trial of renal transplantation: Steroid-free maintenance immunosuppression with calcineurin inhibitor withdrawal after six months associates with improved renal function and reduced chronic histopathology', PLoS ONE, vol. 10, no. 10, e0139247. https://doi.org/10.1371/journal.pone.0139247

Stevens RB, Foster KW, Miles CD, Kalil AC, Florescu DF, Sandoz JP et al. A randomized 2x2 factorial clinical trial of renal transplantation: Steroid-free maintenance immunosuppression with calcineurin inhibitor withdrawal after six months associates with improved renal function and reduced chronic histopathology. PLoS ONE. 2015 Oct 14;10(10):e0139247. doi: 10.1371/journal.pone.0139247

@article{c14ee371bcab4f7492dd7c22d0a7c84a,

title = "A randomized 2x2 factorial clinical trial of renal transplantation: Steroid-free maintenance immunosuppression with calcineurin inhibitor withdrawal after six months associates with improved renal function and reduced chronic histopathology",

author = "Stevens, {R. Brian} and Foster, {Kirk W.} and Miles, {Clifford D.} and Kalil, {Andre C.} and Florescu, {Diana F.} and Sandoz, {John P.} and Rigley, {Theodore H.} and Tamer Malik and Wrenshall, {Lucile E.}",

note = "Publisher Copyright: {\textcopyright} 2015 Stevens et al.This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.",

year = "2015",

month = oct,

day = "14",

doi = "10.1371/journal.pone.0139247",

language = "English",

volume = "10",

journal = "PLoS ONE",

issn = "1932-6203",

number = "10",

}

TY - JOUR

T1 - A randomized 2x2 factorial clinical trial of renal transplantation

T2 - Steroid-free maintenance immunosuppression with calcineurin inhibitor withdrawal after six months associates with improved renal function and reduced chronic histopathology

AU - Stevens, R. Brian

AU - Foster, Kirk W.

AU - Miles, Clifford D.

AU - Kalil, Andre C.

AU - Florescu, Diana F.

AU - Sandoz, John P.

AU - Rigley, Theodore H.

AU - Malik, Tamer

AU - Wrenshall, Lucile E.

N1 - Publisher Copyright: © 2015 Stevens et al.This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PY - 2015/10/14

Y1 - 2015/10/14

UR - http://www.scopus.com/inward/record.url?scp=84949058128&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84949058128&partnerID=8YFLogxK

UR - https://corescholar.libraries.wright.edu/surg/637

U2 - 10.1371/journal.pone.0139247

DO - 10.1371/journal.pone.0139247

M3 - Article

C2 - 26465152

AN - SCOPUS:84949058128

SN - 1932-6203

VL - 10

JO - PLoS ONE

JF - PLoS ONE

IS - 10

M1 - e0139247

ER -

A randomized 2x2 factorial clinical trial of renal transplantation: Steroid-free maintenance immunosuppression with calcineurin inhibitor withdrawal after six months associates with improved renal function and reduced chronic histopathology

ASJC Scopus Subject Areas

Disciplines

Access to Document

Other files and links

Cite this