Antidiabetic and antimalarial biguanide drugs are metal-interactive antiproteolytic agents

Deacon Sweeney, Michael L. Raymer, Thomas D. Lockwood

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)663-677
Number of pages15
JournalBiochemical Pharmacology
Volume66
Issue number4
DOIs
StatePublished - Aug 15 2003

ASJC Scopus Subject Areas

  • Biochemistry
  • Pharmacology

Keywords

  • Cathepsin B
  • Chloroquine
  • Falcipain-2
  • Intracellular protein degradation
  • Metformin
  • Perfused heart
  • Phenformin
  • Proguanil
  • Protease inhibitors

Disciplines

  • Bioinformatics
  • Communication
  • Communication Technology and New Media
  • Computer Sciences
  • Databases and Information Systems
  • Life Sciences
  • OS and Networks
  • Physical Sciences and Mathematics
  • Science and Technology Studies
  • Social and Behavioral Sciences

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