Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population

the Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee

doi:10.1007/s40262-024-01367-2

Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population

the Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee

Pediatrics

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	885-899
Number of pages	15
Journal	Clinical Pharmacokinetics
Volume	63
Issue number	6
DOIs	https://doi.org/10.1007/s40262-024-01367-2
State	Published - Jun 2024

ASJC Scopus Subject Areas

Pharmacology
Pharmacology (medical)

Access to Document

10.1007/s40262-024-01367-2

Cite this

Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population. / the Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee.
In: Clinical Pharmacokinetics, Vol. 63, No. 6, 06.2024, p. 885-899.

Research output: Contribution to journal › Article › peer-review

@article{a9e12094cc7c4102aef5b53fa08c6bd8,

title = "Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population",

author = "\{the Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee\} and Maglalang, \{Patricia D.\} and Jaydeep Sinha and Kanecia Zimmerman and Sean McCann and Andrea Edginton and Hornik, \{Christoph P.\} and Hornik, \{Chi D.\} and Muller, \{William J.\} and Amira Al-Uzri and Marisa Meyer and Chen, \{Jia Yuh\} and Ravinder Anand and Perrin, \{Eliana M.\} and Daniel Gonzalez and Paula Delmore and Sharada Dixit and Joshua Shimizu and Kaylynn Shakespear and Yakub Salman and Priscilla Rosen and Rebbecca Perez and Narus, \{Jo Ann\} and Fumiko Alger and Catherine Sherwin and Michael Spigarelli and Jennifer Talbert and Ashley Mariconti and Janice Bernhardt and Matthew Laughon and Michelle Wiseheart and Jackie Perry and Andrew Michael and Jen Comings and Kelli Brown and Courtney Konow and Susan Poff and Karrie Kernen and Janice Sullivan and Ann, \{D. Pierce\} and Lee Howard and Michelle Hart and Dawn Hansberry and Laura James and Ashlee Parsons and Lisa Petersen and Catherine Tasi and Ramon Adams and Eileen Goldblatt and Brenna Vitou and Eloise Lemon",

note = "Publisher Copyright: {\textcopyright} The Author(s), under exclusive licence to Springer Nature Switzerland AG 2024.",

year = "2024",

month = jun,

doi = "10.1007/s40262-024-01367-2",

language = "English",

volume = "63",

pages = "885--899",

journal = "Clinical Pharmacokinetics",

issn = "0312-5963",

number = "6",

}

TY - JOUR

T1 - Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population

AU - the Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee

AU - Maglalang, Patricia D.

AU - Sinha, Jaydeep

AU - Zimmerman, Kanecia

AU - McCann, Sean

AU - Edginton, Andrea

AU - Hornik, Christoph P.

AU - Hornik, Chi D.

AU - Muller, William J.

AU - Al-Uzri, Amira

AU - Meyer, Marisa

AU - Chen, Jia Yuh

AU - Anand, Ravinder

AU - Perrin, Eliana M.

AU - Gonzalez, Daniel

AU - Delmore, Paula

AU - Dixit, Sharada

AU - Shimizu, Joshua

AU - Shakespear, Kaylynn

AU - Salman, Yakub

AU - Rosen, Priscilla

AU - Perez, Rebbecca

AU - Narus, Jo Ann

AU - Alger, Fumiko

AU - Sherwin, Catherine

AU - Spigarelli, Michael

AU - Talbert, Jennifer

AU - Mariconti, Ashley

AU - Bernhardt, Janice

AU - Laughon, Matthew

AU - Wiseheart, Michelle

AU - Perry, Jackie

AU - Michael, Andrew

AU - Comings, Jen

AU - Brown, Kelli

AU - Konow, Courtney

AU - Poff, Susan

AU - Kernen, Karrie

AU - Sullivan, Janice

AU - Ann, D. Pierce

AU - Howard, Lee

AU - Hart, Michelle

AU - Hansberry, Dawn

AU - James, Laura

AU - Parsons, Ashlee

AU - Petersen, Lisa

AU - Tasi, Catherine

AU - Adams, Ramon

AU - Goldblatt, Eileen

AU - Vitou, Brenna

AU - Lemon, Eloise

PY - 2024/6

Y1 - 2024/6

UR - https://www.scopus.com/pages/publications/85194701803

UR - https://www.scopus.com/inward/citedby.url?scp=85194701803&partnerID=8YFLogxK

U2 - 10.1007/s40262-024-01367-2

DO - 10.1007/s40262-024-01367-2

M3 - Article

C2 - 38814425

AN - SCOPUS:85194701803

SN - 0312-5963

VL - 63

SP - 885

EP - 899

JO - Clinical Pharmacokinetics

JF - Clinical Pharmacokinetics

IS - 6

ER -

Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population

ASJC Scopus Subject Areas

Access to Document

Other files and links

Cite this