CPI203, a BET inhibitor, down-regulates a consistent set of DNA synthesis genes across a wide array of glioblastoma lines

Matthew C. Garrett; Troy Carnwath; Rebecca Albano; Yonghua Zhuang; Catherine A. Behrmann; Merissa Pemberton; Farah Barakat; Robert Lober; Mark Hoeprich; Anthony Paravati; Marilyn Reed; Hailey Spry; Daniel Woo; Eric O’Brien; Brett VanCauwenbergh; John Perentesis; Rani Nasser; Mario Medvedovic; David R. Plas

doi:10.1371/journal.pone.0306846

CPI203, a BET inhibitor, down-regulates a consistent set of DNA synthesis genes across a wide array of glioblastoma lines

Matthew C. Garrett
, Troy Carnwath
, Rebecca Albano
, Yonghua Zhuang
, Catherine A. Behrmann
, Merissa Pemberton
, Farah Barakat
, Robert Lober
, Mark Hoeprich
, Anthony Paravati
, Marilyn Reed
, Hailey Spry
, Daniel Woo
, Eric O’Brien
, Brett VanCauwenbergh
, John Perentesis
, Rani Nasser
, Mario Medvedovic
, David R. Plas

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	e0306846
Journal	PLoS ONE
Volume	20
Issue number	5 May
DOIs	https://doi.org/10.1371/journal.pone.0306846
State	Published - May 2025
Externally published	Yes

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10.1371/journal.pone.0306846

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Garrett, M. C., Carnwath, T., Albano, R., Zhuang, Y., Behrmann, C. A., Pemberton, M., Barakat, F., Lober, R., Hoeprich, M., Paravati, A., Reed, M., Spry, H., Woo, D., O’Brien, E., VanCauwenbergh, B., Perentesis, J., Nasser, R., Medvedovic, M., & Plas, D. R. (2025). CPI203, a BET inhibitor, down-regulates a consistent set of DNA synthesis genes across a wide array of glioblastoma lines. PLoS ONE, 20(5 May), Article e0306846. https://doi.org/10.1371/journal.pone.0306846

Garrett, MC, Carnwath, T, Albano, R, Zhuang, Y, Behrmann, CA, Pemberton, M, Barakat, F, Lober, R, Hoeprich, M, Paravati, A, Reed, M, Spry, H, Woo, D, O’Brien, E, VanCauwenbergh, B, Perentesis, J, Nasser, R, Medvedovic, M & Plas, DR 2025, 'CPI203, a BET inhibitor, down-regulates a consistent set of DNA synthesis genes across a wide array of glioblastoma lines', PLoS ONE, vol. 20, no. 5 May, e0306846. https://doi.org/10.1371/journal.pone.0306846

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AU - Behrmann, Catherine A.

AU - Pemberton, Merissa

AU - Barakat, Farah

AU - Lober, Robert

AU - Hoeprich, Mark

AU - Paravati, Anthony

AU - Reed, Marilyn

AU - Spry, Hailey

AU - Woo, Daniel

AU - O’Brien, Eric

AU - VanCauwenbergh, Brett

AU - Perentesis, John

AU - Nasser, Rani

AU - Medvedovic, Mario

AU - Plas, David R.

N1 - Publisher Copyright: © 2025 Garrett et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PY - 2025/5

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CPI203, a BET inhibitor, down-regulates a consistent set of DNA synthesis genes across a wide array of glioblastoma lines

ASJC Scopus Subject Areas

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