Differences between intertrochanteric and femoral neck fractures in resuscitative status and mortality rates

Introduction: Hip fracture mortality remains a challenge for orthopedic surgeons. The purpose of this study was to compare resuscitative mean arterial pressures (MAPs), intravenous fluid (IVF) administration, and mortality rates between intertrochanteric (IT) and femoral neck (FN) fracture patients. Hypothesis: We hypothesized that IT fracture patients would receive less aggressive fluid resuscitation than FNF patients given the perceived less invasive nature of intra-medullary nails compared with hemiarthroplasty. Materials and methods: An institutional database was queried to identify all hip fractures managed surgically over a 2-year period. Preoperative and intraoperative MAPs and IVF administration, as measures of resuscitation, were compared between IT fracture patients treated with open reduction internal fixation and FN fracture patients treated with hemiarthroplasty. Results: 698 hip fractures, including 531 IT and 167 FN fractures were analyzed. There were no differences between IT and FN fracture cohorts for age, sex distribution, or Charlson Comorbidity Index scores. IT fracture patients were found to have lower MAP upon admission (103.7 ± 20.1 vs. 107.8 ± 18.4 mmHg; p = 0.026), and lower average, minimum, and maximum MAP values preoperatively and intraoperatively. Despite lower MAPs, IT fracture patients received less total IVF (581.9 ± 472.5 vs. 832.9 ± 496.5 cc; p < 0.001) and lower IVF rates intraoperatively (306.5 ± 256.8 vs. 409.8 ± 251.0 cc/hr; p < 0.001). IT fracture patients experienced higher 30-day (7.9% vs. 3.6%; p = 0.040) and 90-day (10.6% vs. 5.4%; p = 0.035) mortality rates and trended towards higher inpatient mortality (3.0% vs. 0.6%; p = 0.088). Multivariate regression demonstrated IT pattern to be independently predictive of 30-day mortality with 2.459 increased odds relative to FN fracture (p = 0.039). Discussion: IT fracture patterns are associated with decreased perioperative MAP values, yet received lower perioperative IVF rates. IT fracture patients suffered higher 30- and 90-day mortality rates, despite similar age and comorbidities. Level of evidence: III; retrospective cohort study.