Effect of Caffeine Consumption on Tissue Oxygen Levels During Hyperbaric Oxygen Treatment

M. Stephens, M. Frey, S. Mohler, Harry J. Khamis, R. Penne, J. Bishop, A. Bowden

Research output: Contribution to journalArticlepeer-review

Abstract

Ten men were exposed to hyperbaric oxygen (HBO 2 ), and their tissue oxygen levels were monitored after they drank either placebo or caffeine beverages. Transcutaneous tissue oxygen (PtcO 2 ) monitor measurements in a normobaric air environment were initially obtained from transducers on the subject's chest and foot. The subjects then consumed either the caffeine (3 mg.kg-1) or the placebo beverage, and after 20 min the subjects were pressurized in a hyperbaric chamber to 2.36 atm abs (1 atm = 101.3250 kPa). The test subjects began breathing 100% oxygen at 2.36 atm abs, 30 min after administration of the experimental beverage, and continued for 30 min, after which the final chest and foot PtcO 2 measurements were recorded (1 h after ingestion of the test drink). Each subject underwent a second hyperbaric exposure during which the alternate drink was administered (either the placebo or the caffeine), and PtcO 2 measurements were again obtained. The increase in right foot PtcO 2 values during HBO 2 exposure was significantly smaller after caffeine consumption than after placebo (P = 0.0018).

Original languageAmerican English
JournalUndersea and Hyperbaric Medicine
Volume26
StatePublished - Jul 1 1999

Disciplines

  • Applied Mathematics
  • Applied Statistics
  • Mathematics
  • Physical Sciences and Mathematics
  • Statistics and Probability

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