Ischemia-Induced Brain Damage is Enhanced in Human Renin and Angiotensinogen Double Transgenic Mice

Shuzhen Chen; Guangze Li; Wenfeng Zhang; Curt D. Sigmund; James E. Olson; Yanfang Chen

doi:10.1161/01.HYP.0000335249.42461.D0

Ischemia-Induced Brain Damage is Enhanced in Human Renin and Angiotensinogen Double Transgenic Mice

Shuzhen Chen, Guangze Li, Wenfeng Zhang, Curt D. Sigmund, James E. Olson, Yanfang Chen

Emergency Medicine

Research output: Contribution to journal › Conference article › peer-review

Original language	American English
Journal	Hypertension
Volume	52
Issue number	4
DOIs	https://doi.org/10.1161/01.HYP.0000335249.42461.D0
State	Published - Oct 2008
Event	62nd Annual High Blood Pressure Conference 2008 - Omni Hotel at CNN Center, Atlanta, United States Duration: Sep 17 2008 → Sep 20 2008 Conference number: 62

Keywords

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Angiotensin II / metabolism
Angiotensin II Type 1 Receptor Blockers / pharmacology
Angiotensinogen / genetics
Angiotensinogen / metabolism*
Animals
Blood Pressure / physiology
Brain / Blood supply
Brain / metabolism*
Brain / phathology
Brain Ischemia / etiology
Brain Ischemia / metabolism*
Brain Ischemia / pathology
Cell Death / pathology
Cell Death / physiology
Disease Models, Animal
Humans
Infraction, Middle Cerebral Artery / complications
Losartan / pharmacology
Male
Mice
Mice, Transgenic
Receptor, Angiotensin, Type 1 / drug effects
Receptor, Angiotensin, Type 1 / metabolism
Regional Blood Flow / physiology
Renin / genetics
Renin / metabolism*
Severity of Illness Index*
Signal Transduction / physiology

Disciplines

Physiological Processes
Medical Neurobiology
Neurosciences
Medical Physiology
Medical Cell Biology

Access to Document

10.1161/01.HYP.0000335249.42461.D0

Cite this

@article{060b1800e00e4f8cb884ebe35a5fe575,

title = "Ischemia-Induced Brain Damage is Enhanced in Human Renin and Angiotensinogen Double Transgenic Mice",

keywords = "Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Angiotensin II / metabolism, Angiotensin II Type 1 Receptor Blockers / pharmacology, Angiotensinogen / genetics, Angiotensinogen / metabolism*, Animals, Blood Pressure / physiology, Brain / Blood supply, Brain / metabolism*, Brain / phathology, Brain Ischemia / etiology, Brain Ischemia / metabolism*, Brain Ischemia / pathology, Cell Death / pathology, Cell Death / physiology, Disease Models, Animal, Humans, Infraction, Middle Cerebral Artery / complications, Losartan / pharmacology, Male, Mice, Mice, Transgenic, Receptor, Angiotensin, Type 1 / drug effects, Receptor, Angiotensin, Type 1 / metabolism, Regional Blood Flow / physiology, Renin / genetics, Renin / metabolism*, Severity of Illness Index*, Signal Transduction / physiology",

author = "Shuzhen Chen and Guangze Li and Wenfeng Zhang and Sigmund, {Curt D.} and Olson, {James E.} and Yanfang Chen",

note = "Presented as a poster; 62nd Annual High Blood Pressure Conference 2008 ; Conference date: 17-09-2008 Through 20-09-2008",

year = "2008",

month = oct,

doi = "10.1161/01.HYP.0000335249.42461.D0",

language = "American English",

volume = "52",

journal = "Hypertension",

issn = "0194-911X",

number = "4",

}

TY - JOUR

T1 - Ischemia-Induced Brain Damage is Enhanced in Human Renin and Angiotensinogen Double Transgenic Mice

AU - Chen, Shuzhen

AU - Li, Guangze

AU - Zhang, Wenfeng

AU - Sigmund, Curt D.

AU - Olson, James E.

AU - Chen, Yanfang

N1 - Conference code: 62

PY - 2008/10

Y1 - 2008/10

KW - Research Support, N.I.H., Extramural

KW - Research Support, Non-U.S. Gov't

KW - Angiotensin II / metabolism

KW - Angiotensin II Type 1 Receptor Blockers / pharmacology

KW - Angiotensinogen / genetics

KW - Angiotensinogen / metabolism

KW - Animals

KW - Blood Pressure / physiology

KW - Brain / Blood supply

KW - Brain / metabolism

KW - Brain / phathology

KW - Brain Ischemia / etiology

KW - Brain Ischemia / metabolism

KW - Brain Ischemia / pathology

KW - Cell Death / pathology

KW - Cell Death / physiology

KW - Disease Models, Animal

KW - Humans

KW - Infraction, Middle Cerebral Artery / complications

KW - Losartan / pharmacology

KW - Male

KW - Mice

KW - Mice, Transgenic

KW - Receptor, Angiotensin, Type 1 / drug effects

KW - Receptor, Angiotensin, Type 1 / metabolism

KW - Regional Blood Flow / physiology

KW - Renin / genetics

KW - Renin / metabolism

KW - Severity of Illness Index

KW - Signal Transduction / physiology

UR - https://corescholar.libraries.wright.edu/ncbp/913

U2 - 10.1161/01.HYP.0000335249.42461.D0

DO - 10.1161/01.HYP.0000335249.42461.D0

M3 - Conference article

SN - 0194-911X

VL - 52

JO - Hypertension

JF - Hypertension

IS - 4

T2 - 62nd Annual High Blood Pressure Conference 2008

Y2 - 17 September 2008 through 20 September 2008

ER -

Ischemia-Induced Brain Damage is Enhanced in Human Renin and Angiotensinogen Double Transgenic Mice

Keywords

Disciplines

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