Low Anti-Tumor Necrosis Factor Levels during Maintenance Phase Are Associated with Treatment Failure in Children with Crohn's Disease

Jonathan Moses; Jeremy Adler; Shehzad A. Saeed; Ann M. Firestine; Joseph A. Galanko; Rana F. Ammoury; Dorsey M. Bass; Julie A. Bass; Monique Bastidas; Keith J. Benkov; Athos Bousvaros; José M. Cabrera; Kelly Y. Chun; Jill M. Dorsey; Dawn R. Ebach; Ajay S. Gulati; Hans H. Herfarth; Anastasia Ivanova; Traci W. Jester; Jess L. Kaplan; Mark E. Kusek; Ian H. Leibowitz; Tiffany M. Linville; Peter A. Margolis; Phillip Minar; Zarela Molle-Rios; Barbara Joanna Niklinska-Schirtz; Kelly K. Olano; Lourdes Osaba; Pablo J. Palomo; Dinesh S. Pashankar; Lisa Pitch; Charles M. Samson; Kelly C. Sandberg; Steven J. Steiner; Jennifer A. Strople; Jillian S. Sullivan; Jeanne Tung; Prateek Wali; David A. Wohl; Mike Zikry; Brendan M. Boyle; Michael D. Kappelman

doi:10.1093/ibd/izae239

Low Anti-Tumor Necrosis Factor Levels during Maintenance Phase Are Associated with Treatment Failure in Children with Crohn's Disease

Jonathan Moses, Jeremy Adler, Shehzad A. Saeed, Ann M. Firestine, Joseph A. Galanko, Rana F. Ammoury, Dorsey M. Bass, Julie A. Bass, Monique Bastidas, Keith J. Benkov, Athos Bousvaros, José M. Cabrera, Kelly Y. Chun, Jill M. Dorsey, Dawn R. Ebach, Ajay S. Gulati, Hans H. Herfarth, Anastasia Ivanova, Traci W. Jester, Jess L. KaplanMark E. Kusek, Ian H. Leibowitz, Tiffany M. Linville, Peter A. Margolis, Phillip Minar, Zarela Molle-Rios, Barbara Joanna Niklinska-Schirtz, Kelly K. Olano, Lourdes Osaba, Pablo J. Palomo, Dinesh S. Pashankar, Lisa Pitch, Charles M. Samson, Kelly C. Sandberg, Steven J. Steiner, Jennifer A. Strople, Jillian S. Sullivan, Jeanne Tung, Prateek Wali, David A. Wohl, Mike Zikry, Brendan M. Boyle, Michael D. Kappelman

Pediatrics

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1841-1850
Number of pages	10
Journal	Inflammatory Bowel Diseases
Volume	31
Issue number	7
DOIs	https://doi.org/10.1093/ibd/izae239
State	Published - Jul 1 2025

ASJC Scopus Subject Areas

Immunology and Allergy
Gastroenterology

Keywords

biologics
inflammatory bowel disease
pediatrics
therapeutic drug monitoring

Access to Document

10.1093/ibd/izae239

Cite this

Moses, J., Adler, J., Saeed, S. A., Firestine, A. M., Galanko, J. A., Ammoury, R. F., Bass, D. M., Bass, J. A., Bastidas, M., Benkov, K. J., Bousvaros, A., Cabrera, J. M., Chun, K. Y., Dorsey, J. M., Ebach, D. R., Gulati, A. S., Herfarth, H. H., Ivanova, A., Jester, T. W., ... Kappelman, M. D. (2025). Low Anti-Tumor Necrosis Factor Levels during Maintenance Phase Are Associated with Treatment Failure in Children with Crohn's Disease. Inflammatory Bowel Diseases, 31(7), 1841-1850. https://doi.org/10.1093/ibd/izae239

Moses, J, Adler, J, Saeed, SA, Firestine, AM, Galanko, JA, Ammoury, RF, Bass, DM, Bass, JA, Bastidas, M, Benkov, KJ, Bousvaros, A, Cabrera, JM, Chun, KY, Dorsey, JM, Ebach, DR, Gulati, AS, Herfarth, HH, Ivanova, A, Jester, TW, Kaplan, JL, Kusek, ME, Leibowitz, IH, Linville, TM, Margolis, PA, Minar, P, Molle-Rios, Z, Niklinska-Schirtz, BJ, Olano, KK, Osaba, L, Palomo, PJ, Pashankar, DS, Pitch, L, Samson, CM, Sandberg, KC, Steiner, SJ, Strople, JA, Sullivan, JS, Tung, J, Wali, P, Wohl, DA, Zikry, M, Boyle, BM & Kappelman, MD 2025, 'Low Anti-Tumor Necrosis Factor Levels during Maintenance Phase Are Associated with Treatment Failure in Children with Crohn's Disease', Inflammatory Bowel Diseases, vol. 31, no. 7, pp. 1841-1850. https://doi.org/10.1093/ibd/izae239

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title = "Low Anti-Tumor Necrosis Factor Levels during Maintenance Phase Are Associated with Treatment Failure in Children with Crohn's Disease",

keywords = "biologics, inflammatory bowel disease, pediatrics, therapeutic drug monitoring",

author = "Jonathan Moses and Jeremy Adler and Saeed, \{Shehzad A.\} and Firestine, \{Ann M.\} and Galanko, \{Joseph A.\} and Ammoury, \{Rana F.\} and Bass, \{Dorsey M.\} and Bass, \{Julie A.\} and Monique Bastidas and Benkov, \{Keith J.\} and Athos Bousvaros and Cabrera, \{Jos{\'e} M.\} and Chun, \{Kelly Y.\} and Dorsey, \{Jill M.\} and Ebach, \{Dawn R.\} and Gulati, \{Ajay S.\} and Herfarth, \{Hans H.\} and Anastasia Ivanova and Jester, \{Traci W.\} and Kaplan, \{Jess L.\} and Kusek, \{Mark E.\} and Leibowitz, \{Ian H.\} and Linville, \{Tiffany M.\} and Margolis, \{Peter A.\} and Phillip Minar and Zarela Molle-Rios and Niklinska-Schirtz, \{Barbara Joanna\} and Olano, \{Kelly K.\} and Lourdes Osaba and Palomo, \{Pablo J.\} and Pashankar, \{Dinesh S.\} and Lisa Pitch and Samson, \{Charles M.\} and Sandberg, \{Kelly C.\} and Steiner, \{Steven J.\} and Strople, \{Jennifer A.\} and Sullivan, \{Jillian S.\} and Jeanne Tung and Prateek Wali and Wohl, \{David A.\} and Mike Zikry and Boyle, \{Brendan M.\} and Kappelman, \{Michael D.\}",

year = "2025",

month = jul,

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doi = "10.1093/ibd/izae239",

language = "English",

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T1 - Low Anti-Tumor Necrosis Factor Levels during Maintenance Phase Are Associated with Treatment Failure in Children with Crohn's Disease

AU - Moses, Jonathan

AU - Adler, Jeremy

AU - Saeed, Shehzad A.

AU - Firestine, Ann M.

AU - Galanko, Joseph A.

AU - Ammoury, Rana F.

AU - Bass, Dorsey M.

AU - Bass, Julie A.

AU - Bastidas, Monique

AU - Benkov, Keith J.

AU - Bousvaros, Athos

AU - Cabrera, José M.

AU - Chun, Kelly Y.

AU - Dorsey, Jill M.

AU - Ebach, Dawn R.

AU - Gulati, Ajay S.

AU - Herfarth, Hans H.

AU - Ivanova, Anastasia

AU - Jester, Traci W.

AU - Kaplan, Jess L.

AU - Kusek, Mark E.

AU - Leibowitz, Ian H.

AU - Linville, Tiffany M.

AU - Margolis, Peter A.

AU - Minar, Phillip

AU - Molle-Rios, Zarela

AU - Niklinska-Schirtz, Barbara Joanna

AU - Olano, Kelly K.

AU - Osaba, Lourdes

AU - Palomo, Pablo J.

AU - Pashankar, Dinesh S.

AU - Pitch, Lisa

AU - Samson, Charles M.

AU - Sandberg, Kelly C.

AU - Steiner, Steven J.

AU - Strople, Jennifer A.

AU - Sullivan, Jillian S.

AU - Tung, Jeanne

AU - Wali, Prateek

AU - Wohl, David A.

AU - Zikry, Mike

AU - Boyle, Brendan M.

AU - Kappelman, Michael D.

PY - 2025/7/1

Y1 - 2025/7/1

KW - biologics

KW - inflammatory bowel disease

KW - pediatrics

KW - therapeutic drug monitoring

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AN - SCOPUS:105010241674

SN - 1078-0998

VL - 31

SP - 1841

EP - 1850

JO - Inflammatory Bowel Diseases

JF - Inflammatory Bowel Diseases

IS - 7

ER -

Low Anti-Tumor Necrosis Factor Levels during Maintenance Phase Are Associated with Treatment Failure in Children with Crohn's Disease

ASJC Scopus Subject Areas

Keywords

Access to Document

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