Model of the developing tumorigenic phenotype in mammalian cells and the roles of sustained stress and replicative senescence

Tatiana V. Karpinets, Brent D. Foy

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)253-264
Number of pages12
JournalJournal of Theoretical Biology
Volume227
Issue number2
DOIs
StatePublished - Mar 21 2004
Externally publishedYes

ASJC Scopus Subject Areas

  • Statistics and Probability
  • Modeling and Simulation
  • General Biochemistry,Genetics and Molecular Biology
  • General Immunology and Microbiology
  • General Agricultural and Biological Sciences
  • Applied Mathematics

Keywords

  • Apoptosis
  • Cancer
  • Cellular senescence
  • Genomic instability
  • Stress response
  • Tumorigenesis

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