PCOS from Conception to Menopause: A Review of Our Current Understanding

Leah D. Whigham, michelle L. Durant, Jerome L. Yaklic, Steven R. Lindheim

Research output: Contribution to journalArticlepeer-review

Abstract

Polycystic ovary syndrome (PCOS) appears to be a part of a lifelong continuum starting in utero, with progressive signs in the adolescent female. It is recognized as the most common endocrinopathy in reproductive age women, and may have sequelae in the menopausal PCOS woman. PCOS is a disorder characterized by hyperandrogenism and chronic anovulation affecting at least 1 in 15 women or approximately 6-7% of reproductive age women. Metabolic and health complications associated with PCOS include obesity, insulin resistance, dyslipidemia, pancreatic beta-cell dysfunction, type 2 diabetes, cardiovascular disease, endometrial cancer, sleep apnea, inflammation, and infertility.

Original languageAmerican English
JournalAndrology and Gynecology: Current Research
Volume3
StatePublished - Jan 1 2014

Keywords

  • Anti-Mullerian Hormone
  • Hirsutism
  • Hyperandrogenism
  • Oligomenorrhea
  • PCOS

Disciplines

  • Medical Specialties
  • Medicine and Health Sciences
  • Obstetrics and Gynecology

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