Phosphoglycan Messengers and Their Medical Uses (SLE)

Khalid M. Elased; Khalid A. Gumaa; Hassan Rahmoune; Thomas Rademacher; J. B. De Souza

Phosphoglycan Messengers and Their Medical Uses (SLE)

Khalid M. Elased, Khalid A. Gumaa, Hassan Rahmoune, Thomas Rademacher, J. B. De Souza

Wright State University

Research output: Other contribution

Abstract

PPhosphoglycan messengers (PGMs) which are carbohydrate derivatised phosphatidyl cyclitols are disclosed, together with the finding that these substances are biologically active, especially in modulating plasma cholesterol, plasma triglycerides and/or high density lipoprotein levels and/or modulating the LDL:HDL ratio, and for the treatment of lipodystrophy or dyslipidemia. These compounds are distinct from GPI-anchors disclosed in the prior art as these GPI-anchors are protein linked and are not biologically active.

Original language	American English
State	Published - Jan 3 2002

Disciplines

Chemicals and Drugs
Medical Toxicology
Medicine and Health Sciences

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Phosphoglycan Messengers and Their Medical Uses (SLE)Final published version, 1 MBLicense: Unspecified

https://www.google.com/patents/WO2002000674A1

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title = "Phosphoglycan Messengers and Their Medical Uses (SLE)",

abstract = " PPhosphoglycan messengers (PGMs) which are carbohydrate derivatised phosphatidyl cyclitols are disclosed, together with the finding that these substances are biologically active, especially in modulating plasma cholesterol, plasma triglycerides and/or high density lipoprotein levels and/or modulating the LDL:HDL ratio, and for the treatment of lipodystrophy or dyslipidemia. These compounds are distinct from GPI-anchors disclosed in the prior art as these GPI-anchors are protein linked and are not biologically active.",

author = "Elased, {Khalid M.} and Gumaa, {Khalid A.} and Hassan Rahmoune and Thomas Rademacher and {De Souza}, {J. B.}",

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TY - GEN

T1 - Phosphoglycan Messengers and Their Medical Uses (SLE)

AU - Elased, Khalid M.

AU - Gumaa, Khalid A.

AU - Rahmoune, Hassan

AU - Rademacher, Thomas

AU - De Souza, J. B.

PY - 2002/1/3

Y1 - 2002/1/3

N2 - PPhosphoglycan messengers (PGMs) which are carbohydrate derivatised phosphatidyl cyclitols are disclosed, together with the finding that these substances are biologically active, especially in modulating plasma cholesterol, plasma triglycerides and/or high density lipoprotein levels and/or modulating the LDL:HDL ratio, and for the treatment of lipodystrophy or dyslipidemia. These compounds are distinct from GPI-anchors disclosed in the prior art as these GPI-anchors are protein linked and are not biologically active.

AB - PPhosphoglycan messengers (PGMs) which are carbohydrate derivatised phosphatidyl cyclitols are disclosed, together with the finding that these substances are biologically active, especially in modulating plasma cholesterol, plasma triglycerides and/or high density lipoprotein levels and/or modulating the LDL:HDL ratio, and for the treatment of lipodystrophy or dyslipidemia. These compounds are distinct from GPI-anchors disclosed in the prior art as these GPI-anchors are protein linked and are not biologically active.

UR - https://corescholar.libraries.wright.edu/ptox/146

M3 - Other contribution

ER -

Phosphoglycan Messengers and Their Medical Uses (SLE)

Abstract

Disciplines

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