Placental Hypoxia-Inducible Factor 1 Alpha in Early-Onset Preeclampsia as a Predictor of Future Risk in Maternal and Fetal Health

Julie Slyby; Bryce Linkous; Sarah Scott; Chandni Chandiramani; Amy Hwang; Danielle Spanbauer; Melissa R. Kaufman; Traci Rackett; Kailey Nolan; Emily Stone; Rose A Maxwell; David N. Dhanraj; Thomas L. Brown

Placental Hypoxia-Inducible Factor 1 Alpha in Early-Onset Preeclampsia as a Predictor of Future Risk in Maternal and Fetal Health

Julie Slyby, Bryce Linkous, Sarah Scott, Chandni Chandiramani, Amy Hwang, Danielle Spanbauer, Melissa R. Kaufman, Traci Rackett, Kailey Nolan, Emily Stone, Rose A Maxwell, David N. Dhanraj, Thomas L. Brown

Research output: Contribution to conference › Poster › peer-review

Abstract

Preeclampsia is a life-threatening, pregnancy-associated disorder characterized by the rapid development of hypertension with renal dysfunction. While preeclampsia generally occurs later in pregnancy, early-onset preeclampsia (EOPE) can occur much earlier and is usually more devastating. Early-onset preeclampsia is also associated with an increased risk of maternal cardiovascular and metabolic disease in mothers later in life and neurocognitive dysfunction in their offspring. EOPE is strongly associated with abnormal placental development and fetal growth restriction during pregnancy.

Original language	American English
State	Published - Apr 30 2021
Event	2021 Boonshoft School of Medicine Medical Student Research Symposium Abstracts and Posters - Virtual Duration: Apr 29 2021 → Apr 29 2021

Conference

Conference	2021 Boonshoft School of Medicine Medical Student Research Symposium Abstracts and Posters
Period	4/29/21 → 4/29/21

Keywords

Placental Hypoxia
Early-Onset Preeclampsia
Factor 1 Alpha
Female
Adult
pregnancy

Disciplines

Medical Education
Obstetrics and Gynecology

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Placental Hypoxia-Inducible Factor 1 Alpha in Early-Onset PreeclaFinal published version, 457 KBLicense: CC BY

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Slyby, J., Linkous, B., Scott, S., Chandiramani, C., Hwang, A., Spanbauer, D., Kaufman, M. R., Rackett, T., Nolan, K., Stone, E., Maxwell, R. A., Dhanraj, D. N., & Brown, T. L. (2021). Placental Hypoxia-Inducible Factor 1 Alpha in Early-Onset Preeclampsia as a Predictor of Future Risk in Maternal and Fetal Health. Poster session presented at 2021 Boonshoft School of Medicine Medical Student Research Symposium Abstracts and Posters.

Placental Hypoxia-Inducible Factor 1 Alpha in Early-Onset Preeclampsia as a Predictor of Future Risk in Maternal and Fetal Health. / Slyby, Julie; Linkous, Bryce; Scott, Sarah et al.
2021. Poster session presented at 2021 Boonshoft School of Medicine Medical Student Research Symposium Abstracts and Posters.

Research output: Contribution to conference › Poster › peer-review

Slyby, J, Linkous, B, Scott, S, Chandiramani, C, Hwang, A, Spanbauer, D, Kaufman, MR, Rackett, T, Nolan, K, Stone, E, Maxwell, RA, Dhanraj, DN & Brown, TL 2021, 'Placental Hypoxia-Inducible Factor 1 Alpha in Early-Onset Preeclampsia as a Predictor of Future Risk in Maternal and Fetal Health', 2021 Boonshoft School of Medicine Medical Student Research Symposium Abstracts and Posters, 4/29/21 - 4/29/21.

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title = "Placental Hypoxia-Inducible Factor 1 Alpha in Early-Onset Preeclampsia as a Predictor of Future Risk in Maternal and Fetal Health",

abstract = " Preeclampsia is a life-threatening, pregnancy-associated disorder characterized by the rapid development of hypertension with renal dysfunction. While preeclampsia generally occurs later in pregnancy, early-onset preeclampsia (EOPE) can occur much earlier and is usually more devastating. Early-onset preeclampsia is also associated with an increased risk of maternal cardiovascular and metabolic disease in mothers later in life and neurocognitive dysfunction in their offspring. EOPE is strongly associated with abnormal placental development and fetal growth restriction during pregnancy.",

keywords = "Placental Hypoxia, Early-Onset Preeclampsia, Factor 1 Alpha, Female, Adult, pregnancy",

author = "Julie Slyby and Bryce Linkous and Sarah Scott and Chandni Chandiramani and Amy Hwang and Danielle Spanbauer and Kaufman, {Melissa R.} and Traci Rackett and Kailey Nolan and Emily Stone and Maxwell, {Rose A} and Dhanraj, {David N.} and Brown, {Thomas L.}",

year = "2021",

month = apr,

day = "30",

language = "American English",

note = "2021 Boonshoft School of Medicine Medical Student Research Symposium Abstracts and Posters ; Conference date: 29-04-2021 Through 29-04-2021",

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T1 - Placental Hypoxia-Inducible Factor 1 Alpha in Early-Onset Preeclampsia as a Predictor of Future Risk in Maternal and Fetal Health

AU - Slyby, Julie

AU - Linkous, Bryce

AU - Scott, Sarah

AU - Chandiramani, Chandni

AU - Hwang, Amy

AU - Spanbauer, Danielle

AU - Kaufman, Melissa R.

AU - Rackett, Traci

AU - Nolan, Kailey

AU - Stone, Emily

AU - Maxwell, Rose A

AU - Dhanraj, David N.

AU - Brown, Thomas L.

PY - 2021/4/30

Y1 - 2021/4/30

N2 - Preeclampsia is a life-threatening, pregnancy-associated disorder characterized by the rapid development of hypertension with renal dysfunction. While preeclampsia generally occurs later in pregnancy, early-onset preeclampsia (EOPE) can occur much earlier and is usually more devastating. Early-onset preeclampsia is also associated with an increased risk of maternal cardiovascular and metabolic disease in mothers later in life and neurocognitive dysfunction in their offspring. EOPE is strongly associated with abnormal placental development and fetal growth restriction during pregnancy.

AB - Preeclampsia is a life-threatening, pregnancy-associated disorder characterized by the rapid development of hypertension with renal dysfunction. While preeclampsia generally occurs later in pregnancy, early-onset preeclampsia (EOPE) can occur much earlier and is usually more devastating. Early-onset preeclampsia is also associated with an increased risk of maternal cardiovascular and metabolic disease in mothers later in life and neurocognitive dysfunction in their offspring. EOPE is strongly associated with abnormal placental development and fetal growth restriction during pregnancy.

KW - Placental Hypoxia

KW - Early-Onset Preeclampsia

KW - Factor 1 Alpha

KW - Female

KW - Adult

KW - pregnancy

UR - https://corescholar.libraries.wright.edu/msrs/2021/poster_presentations_5/1

M3 - Poster

T2 - 2021 Boonshoft School of Medicine Medical Student Research Symposium Abstracts and Posters

Y2 - 29 April 2021 through 29 April 2021

ER -

Placental Hypoxia-Inducible Factor 1 Alpha in Early-Onset Preeclampsia as a Predictor of Future Risk in Maternal and Fetal Health

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