Predicting conserved water-mediated and polar ligand interactions in proteins using a k-nearest-neighbors genetic algorithm

Michael L. Raymer, Paul C. Sanschagrin, William F. Punch, Sridhar Venkataraman, Erik D. Goodman, Leslie A. Kuhn

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)445-464
Number of pages20
JournalJournal of Molecular Biology
Volume265
Issue number4
DOIs
StatePublished - Jan 31 1997

ASJC Scopus Subject Areas

  • Biophysics
  • Structural Biology
  • Molecular Biology

Keywords

  • Drug design
  • Hydration
  • Protein recognition
  • Solvent modeling
  • Water site prediction

Disciplines

  • Bioinformatics
  • Communication
  • Communication Technology and New Media
  • Computer Sciences
  • Databases and Information Systems
  • Life Sciences
  • OS and Networks
  • Physical Sciences and Mathematics
  • Science and Technology Studies
  • Social and Behavioral Sciences

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