Sleep Propensity and Sleep Apnea-Specific Hypoxia Are Associated With Excessive Daytime Sleepiness

Reza Sadeghi; MK Younes; S. A. Sands; L. T. Taranto-Montemurro; S. Bertisch; D. A. Wellman; S. S. Redline; Tanvi Banerjee; A. Azarbarzin

doi:10.1164/ajrccm-conference.2020.201.1_MeetingAbstracts.A2704

Sleep Propensity and Sleep Apnea-Specific Hypoxia Are Associated With Excessive Daytime Sleepiness

Reza Sadeghi, MK Younes, S. A. Sands, L. T. Taranto-Montemurro, S. Bertisch, D. A. Wellman, S. S. Redline, Tanvi Banerjee, A. Azarbarzin

Wright State University

Research output: Contribution to journal › Article › peer-review

Abstract

Excessive daytime sleepiness is a hallmark of obstructive sleep apnea (OSA). Previous research reports substantial variability in patient-reported sleepiness for a given OSA severity, i.e., apnea-hypopnea index (AHI). This may be partly due to inadequate characterization of intermittent hypoxia or a physiologic disorder involving the central nervous system (sleep propensity, Fernandez-Mendoza et al. 2015; e.g. daytime sleepiness is more common in individuals with dementia). We assessed the separate associations between respiratory event- related desaturation, as a measure of intermittent hypoxia, and sleep depth on daytime sleepiness.

Original language	American English
Journal	American Thoracic Society 2020 International Conference
Volume	2020
DOIs	https://doi.org/10.1164/ajrccm-conference.2020.201.1_MeetingAbstracts.A2704
State	Published - May 1 2020

Keywords

Excessive daytime sleepiness
Obstructive sleep apnea
Sleep apena syndromes

Disciplines

Computer Sciences
Engineering

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https://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2020.201.1_MeetingAbstracts.A2704

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Sadeghi, R., Younes, MK., Sands, S. A., Taranto-Montemurro, L. T., Bertisch, S., Wellman, D. A., Redline, S. S., Banerjee, T., & Azarbarzin, A. (2020). Sleep Propensity and Sleep Apnea-Specific Hypoxia Are Associated With Excessive Daytime Sleepiness. American Thoracic Society 2020 International Conference, 2020. https://doi.org/10.1164/ajrccm-conference.2020.201.1_MeetingAbstracts.A2704

Sadeghi, R, Younes, MK, Sands, SA, Taranto-Montemurro, LT, Bertisch, S, Wellman, DA, Redline, SS, Banerjee, T & Azarbarzin, A 2020, 'Sleep Propensity and Sleep Apnea-Specific Hypoxia Are Associated With Excessive Daytime Sleepiness', American Thoracic Society 2020 International Conference, vol. 2020. https://doi.org/10.1164/ajrccm-conference.2020.201.1_MeetingAbstracts.A2704

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abstract = "Excessive daytime sleepiness is a hallmark of obstructive sleep apnea (OSA). Previous research reports substantial variability in patient-reported sleepiness for a given OSA severity, i.e., apnea-hypopnea index (AHI). This may be partly due to inadequate characterization of intermittent hypoxia or a physiologic disorder involving the central nervous system (sleep propensity, Fernandez-Mendoza et al. 2015; e.g. daytime sleepiness is more common in individuals with dementia). We assessed the separate associations between respiratory event- related desaturation, as a measure of intermittent hypoxia, and sleep depth on daytime sleepiness.",

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T1 - Sleep Propensity and Sleep Apnea-Specific Hypoxia Are Associated With Excessive Daytime Sleepiness

AU - Sadeghi, Reza

AU - Younes, MK

AU - Sands, S. A.

AU - Taranto-Montemurro, L. T.

AU - Bertisch, S.

AU - Wellman, D. A.

AU - Redline, S. S.

AU - Banerjee, Tanvi

AU - Azarbarzin, A.

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N2 - Excessive daytime sleepiness is a hallmark of obstructive sleep apnea (OSA). Previous research reports substantial variability in patient-reported sleepiness for a given OSA severity, i.e., apnea-hypopnea index (AHI). This may be partly due to inadequate characterization of intermittent hypoxia or a physiologic disorder involving the central nervous system (sleep propensity, Fernandez-Mendoza et al. 2015; e.g. daytime sleepiness is more common in individuals with dementia). We assessed the separate associations between respiratory event- related desaturation, as a measure of intermittent hypoxia, and sleep depth on daytime sleepiness.

AB - Excessive daytime sleepiness is a hallmark of obstructive sleep apnea (OSA). Previous research reports substantial variability in patient-reported sleepiness for a given OSA severity, i.e., apnea-hypopnea index (AHI). This may be partly due to inadequate characterization of intermittent hypoxia or a physiologic disorder involving the central nervous system (sleep propensity, Fernandez-Mendoza et al. 2015; e.g. daytime sleepiness is more common in individuals with dementia). We assessed the separate associations between respiratory event- related desaturation, as a measure of intermittent hypoxia, and sleep depth on daytime sleepiness.

KW - Excessive daytime sleepiness

KW - Obstructive sleep apnea

KW - Sleep apena syndromes

UR - https://corescholar.libraries.wright.edu/cse/644

UR - https://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2020.201.1_MeetingAbstracts.A2704

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DO - 10.1164/ajrccm-conference.2020.201.1_MeetingAbstracts.A2704

M3 - Article

VL - 2020

JO - American Thoracic Society 2020 International Conference

JF - American Thoracic Society 2020 International Conference

ER -

Sleep Propensity and Sleep Apnea-Specific Hypoxia Are Associated With Excessive Daytime Sleepiness

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Keywords

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