State of Ohio Adversity and Resilience (SOAR) study protocol: a comprehensive, multimodal, family-based, longitudinal observational investigation of risk and resilience in mental health and substance use disorders

Anthony P. King; Scott Langenecker; Stephanie M. Gorka; Jessica Turner; Lei Wang; Heather Wastler; Marybel Gonzalez; Lisa M. Christian; Canada Keck; Randall Olsen; Hyoshin Kim; Brett Klamer; Soledad Fernandez; Caleb Adler; Elissar Andari; Stacey L. Barrenger; Natalie Bonfine; Melanie Bozzay; Susan L. Brown; Christopher Browning; Katie Burkhouse; Kathleen Carter; Kim Cecil; Karin G. Coifman; Emil Coccaro; Timothy N. Crawford; Cory Cronin; Melissa Delbello; Anne Marie Duchemin; Steven W. Evans; Chris Flask; K. Jean Forney; Larrilyn Grant; John Gunstad; Paul J. Hershberger; Kristen R. Hoskinson; Christina Klein; Sara Koenig; Molly Mcvoy; Paula K. Miller; Jose Moreno; Eric E. Nelson; Randolph Nesse; Christopher Nguyen; Kei Nomaguchi; Alissa Paolella; Edison Perdomo; Colin Odden; Martha Sajatovic; Robert Mccullumsmith; Jonathan Trauth; Ivy Tso; Xin Wang; Jennifer T. Weinandy; Krista K. Westrick-Payne; Greta Winbush; Brian T. Wymbs; Hong Xie; Steve Gavazzi; Timothy R. Huerta; Grace Maynard-Wentzel; Nina Kraguljac; K. Luan Phan

doi:10.1136/bmjopen-2025-099525

State of Ohio Adversity and Resilience (SOAR) study protocol: a comprehensive, multimodal, family-based, longitudinal observational investigation of risk and resilience in mental health and substance use disorders

Anthony P. King
, Scott Langenecker
, Stephanie M. Gorka
, Jessica Turner
, Lei Wang
, Heather Wastler
, Marybel Gonzalez
, Lisa M. Christian
, Canada Keck
, Randall Olsen
, Hyoshin Kim
, Brett Klamer
, Soledad Fernandez
, Caleb Adler
, Elissar Andari
, Stacey L. Barrenger
, Natalie Bonfine
, Melanie Bozzay
, Susan L. Brown
, Christopher Browning

Katie Burkhouse, Kathleen Carter, Kim Cecil, Karin G. Coifman, Emil Coccaro, Timothy N. Crawford, Cory Cronin, Melissa Delbello, Anne Marie Duchemin, Steven W. Evans, Chris Flask, K. Jean Forney, Larrilyn Grant, John Gunstad, Paul J. Hershberger, Kristen R. Hoskinson, Christina Klein, Sara Koenig, Molly Mcvoy, Paula K. Miller, Jose Moreno, Eric E. Nelson, Randolph Nesse, Christopher Nguyen, Kei Nomaguchi, Alissa Paolella, Edison Perdomo, Colin Odden, Martha Sajatovic, Robert Mccullumsmith, Jonathan Trauth, Ivy Tso, Xin Wang, Jennifer T. Weinandy, Krista K. Westrick-Payne, Greta Winbush, Brian T. Wymbs, Hong Xie, Steve Gavazzi, Timothy R. Huerta, Grace Maynard-Wentzel, Nina Kraguljac, K. Luan Phan

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	e099525
Journal	BMJ Open
Volume	15
Issue number	11
DOIs	https://doi.org/10.1136/bmjopen-2025-099525
State	Published - Nov 19 2025

ASJC Scopus Subject Areas

General Medicine

Keywords

EPIDEMIOLOGIC STUDIES
MENTAL HEALTH
Neurobiology
Risk Factors
Substance misuse
Suicide & self-harm

Access to Document

10.1136/bmjopen-2025-099525

Cite this

King, A. P., Langenecker, S., Gorka, S. M., Turner, J., Wang, L., Wastler, H., Gonzalez, M., Christian, L. M., Keck, C., Olsen, R., Kim, H., Klamer, B., Fernandez, S., Adler, C., Andari, E., Barrenger, S. L., Bonfine, N., Bozzay, M., Brown, S. L., ... Phan, K. L. (2025). State of Ohio Adversity and Resilience (SOAR) study protocol: a comprehensive, multimodal, family-based, longitudinal observational investigation of risk and resilience in mental health and substance use disorders. BMJ Open, 15(11), Article e099525. https://doi.org/10.1136/bmjopen-2025-099525

State of Ohio Adversity and Resilience (SOAR) study protocol: a comprehensive, multimodal, family-based, longitudinal observational investigation of risk and resilience in mental health and substance use disorders. / King, Anthony P.; Langenecker, Scott; Gorka, Stephanie M. et al.
In: BMJ Open, Vol. 15, No. 11, e099525, 19.11.2025.

Research output: Contribution to journal › Article › peer-review

King, AP, Langenecker, S, Gorka, SM, Turner, J, Wang, L, Wastler, H, Gonzalez, M, Christian, LM, Keck, C, Olsen, R, Kim, H, Klamer, B, Fernandez, S, Adler, C, Andari, E, Barrenger, SL, Bonfine, N, Bozzay, M, Brown, SL, Browning, C, Burkhouse, K, Carter, K, Cecil, K, Coifman, KG, Coccaro, E, Crawford, TN, Cronin, C, Delbello, M, Duchemin, AM, Evans, SW, Flask, C, Forney, KJ, Grant, L, Gunstad, J, Hershberger, PJ, Hoskinson, KR, Klein, C, Koenig, S, Mcvoy, M, Miller, PK, Moreno, J, Nelson, EE, Nesse, R, Nguyen, C, Nomaguchi, K, Paolella, A, Perdomo, E, Odden, C, Sajatovic, M, Mccullumsmith, R, Trauth, J, Tso, I, Wang, X, Weinandy, JT, Westrick-Payne, KK, Winbush, G, Wymbs, BT, Xie, H, Gavazzi, S, Huerta, TR, Maynard-Wentzel, G, Kraguljac, N & Phan, KL 2025, 'State of Ohio Adversity and Resilience (SOAR) study protocol: a comprehensive, multimodal, family-based, longitudinal observational investigation of risk and resilience in mental health and substance use disorders', BMJ Open, vol. 15, no. 11, e099525. https://doi.org/10.1136/bmjopen-2025-099525

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title = "State of Ohio Adversity and Resilience (SOAR) study protocol: a comprehensive, multimodal, family-based, longitudinal observational investigation of risk and resilience in mental health and substance use disorders",

keywords = "EPIDEMIOLOGIC STUDIES, MENTAL HEALTH, Neurobiology, Risk Factors, Substance misuse, Suicide \& self-harm",

author = "King, \{Anthony P.\} and Scott Langenecker and Gorka, \{Stephanie M.\} and Jessica Turner and Lei Wang and Heather Wastler and Marybel Gonzalez and Christian, \{Lisa M.\} and Canada Keck and Randall Olsen and Hyoshin Kim and Brett Klamer and Soledad Fernandez and Caleb Adler and Elissar Andari and Barrenger, \{Stacey L.\} and Natalie Bonfine and Melanie Bozzay and Brown, \{Susan L.\} and Christopher Browning and Katie Burkhouse and Kathleen Carter and Kim Cecil and Coifman, \{Karin G.\} and Emil Coccaro and Crawford, \{Timothy N.\} and Cory Cronin and Melissa Delbello and Duchemin, \{Anne Marie\} and Evans, \{Steven W.\} and Chris Flask and Forney, \{K. Jean\} and Larrilyn Grant and John Gunstad and Hershberger, \{Paul J.\} and Hoskinson, \{Kristen R.\} and Christina Klein and Sara Koenig and Molly Mcvoy and Miller, \{Paula K.\} and Jose Moreno and Nelson, \{Eric E.\} and Randolph Nesse and Christopher Nguyen and Kei Nomaguchi and Alissa Paolella and Edison Perdomo and Colin Odden and Martha Sajatovic and Robert Mccullumsmith and Jonathan Trauth and Ivy Tso and Xin Wang and Weinandy, \{Jennifer T.\} and Westrick-Payne, \{Krista K.\} and Greta Winbush and Wymbs, \{Brian T.\} and Hong Xie and Steve Gavazzi and Huerta, \{Timothy R.\} and Grace Maynard-Wentzel and Nina Kraguljac and Phan, \{K. Luan\}",

note = "Publisher Copyright: {\textcopyright} Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group.",

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doi = "10.1136/bmjopen-2025-099525",

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AU - King, Anthony P.

AU - Langenecker, Scott

AU - Gorka, Stephanie M.

AU - Turner, Jessica

AU - Wang, Lei

AU - Wastler, Heather

AU - Gonzalez, Marybel

AU - Christian, Lisa M.

AU - Keck, Canada

AU - Olsen, Randall

AU - Kim, Hyoshin

AU - Klamer, Brett

AU - Fernandez, Soledad

AU - Adler, Caleb

AU - Andari, Elissar

AU - Barrenger, Stacey L.

AU - Bonfine, Natalie

AU - Bozzay, Melanie

AU - Brown, Susan L.

AU - Browning, Christopher

AU - Burkhouse, Katie

AU - Carter, Kathleen

AU - Cecil, Kim

AU - Coifman, Karin G.

AU - Coccaro, Emil

AU - Crawford, Timothy N.

AU - Cronin, Cory

AU - Delbello, Melissa

AU - Duchemin, Anne Marie

AU - Evans, Steven W.

AU - Flask, Chris

AU - Forney, K. Jean

AU - Grant, Larrilyn

AU - Gunstad, John

AU - Hershberger, Paul J.

AU - Hoskinson, Kristen R.

AU - Klein, Christina

AU - Koenig, Sara

AU - Mcvoy, Molly

AU - Miller, Paula K.

AU - Moreno, Jose

AU - Nelson, Eric E.

AU - Nesse, Randolph

AU - Nguyen, Christopher

AU - Nomaguchi, Kei

AU - Paolella, Alissa

AU - Perdomo, Edison

AU - Odden, Colin

AU - Sajatovic, Martha

AU - Mccullumsmith, Robert

AU - Trauth, Jonathan

AU - Tso, Ivy

AU - Wang, Xin

AU - Weinandy, Jennifer T.

AU - Westrick-Payne, Krista K.

AU - Winbush, Greta

AU - Wymbs, Brian T.

AU - Xie, Hong

AU - Gavazzi, Steve

AU - Huerta, Timothy R.

AU - Maynard-Wentzel, Grace

AU - Kraguljac, Nina

AU - Phan, K. Luan

PY - 2025/11/19

Y1 - 2025/11/19

KW - EPIDEMIOLOGIC STUDIES

KW - MENTAL HEALTH

KW - Neurobiology

KW - Risk Factors

KW - Substance misuse

KW - Suicide & self-harm

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UR - https://www.scopus.com/pages/publications/105022500384#tab=citedBy

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SN - 2044-6055

VL - 15

JO - BMJ Open

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ER -

State of Ohio Adversity and Resilience (SOAR) study protocol: a comprehensive, multimodal, family-based, longitudinal observational investigation of risk and resilience in mental health and substance use disorders

ASJC Scopus Subject Areas

Keywords

Access to Document

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