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Trophoblast-specific overexpression of Slc7a5 increases fetal amino acid availability and hepatic mTOR signalling and causes increased fetal growth

  • Fredrick J. Rosario
  • , Hiroshi Shimada
  • , Sam Blessen J. Fredrick
  • , Kenneth Barentsen
  • , Theresa L. Powell
  • , Johann Urschitz
  • , Thomas L. Brown
  • , Laura Brown
  • , Thomas Jansson

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)2276-2301
Number of pages26
JournalThe Journal of Physiology
Volume604
Issue number5
DOIs
StatePublished - Mar 1 2026
Externally publishedYes

ASJC Scopus Subject Areas

  • Physiology

Keywords

  • fetal development
  • leucine
  • maternal–fetal exchange
  • mechanistic target of rapamycin
  • placenta
  • pregnancy complications

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